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Metabolomic Assays of Postmortem Brain Extracts: Pitfalls in Extrapolation of Concentrations of Glucose and Amino Acids to Metabolic Dysregulation In Vivo in Neurological Diseases
Authors:Dienel  Gerald A.
Affiliation:1.Department of Neurology, University of Arkansas for Medical Sciences, 4301 W. Markham St., Slot 500, Little Rock, AR, 72205, USA
;2.Department of Cell Biology and Physiology, University of New Mexico, Albuquerque, NM, 87131, USA
;
Abstract:Neurochemical Research - Glucose utilization is reduced in vulnerable brain regions affected by neurological disorders, especially Alzheimer’s disease (AD), but the basis for abnormal glucose...
Keywords:
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