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Ibuprofen Exerts Antiepileptic and Neuroprotective Effects in the Rat Model of Pentylenetetrazol-Induced Epilepsy via the COX-2/NLRP3/IL-18 Pathway
Authors:Liu  Rui  Wu  Shuhua  Guo  Chong  Hu  Zhongbo  Peng  Jiangtao  Guo  Ke  Zhang  Xinfan  Li  Jianmin
Institution:1.Department of Neurosurgery, Binzhou Medical University Hospital, Binzhou, 256603, Shandong, China
;2.Department of Pathology, Binzhou Medical University Hospital, Binzhou, 256603, Shandong, China
;
Abstract:Neurochemical Research - Epilepsy is one of the most common diseases of the central nervous system. Recent studies have shown that a variety of inflammatory mediators play a key role in the...
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