The bursa of Fabricius: a central organ providing for contact between the lymphoid system and intestinal content |
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| Authors: | T Schaffner J Mueller M W Hess H Cottier B Sordat C Ropke |
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| Affiliation: | 1. Department of Pathology, University of Bern, and the Swiss Institute of Experimental Cancer Research, Lausanne, Switzerland;2. The Institute for Medical Anatomy, University of Copenhague, Denmark |
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| Abstract: | Small inert particles, after oral or intracloacal administration to chickens, are readily taken up and deposited throughout the medullary portion of bursal follicles. Epithelial tuft cells transporting this material are distinctively equipped with lytic enzymes. No entry of living bacteria into the lymphoid tissue was observed. These findings are indicative of an antigen-driven development of the bursal system protected by local bactericidal mechanisms. |
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