Abstract: | Temporal summation of monosynaptic EPSP produced by paired afferent stimuli was investigated during experiments on identified neurons of the molluskPlanorbis corneus. Summation follows a nonlinear pattern in these neurons and falls into three categories — facilitatory, depressive, and mixed. Summation functions (ratio between test and conditioning EPSP amplitudes expressed as a function of length of interstimulus interval) displayed some local maximum in most instances. Length of the interstimulus interval corresponding to this maximum correlates with the parameters of single EPSP. The possible location of mechanisms underlying the observed characteristics of EPSP summation is discussed.A. A. Bogomolets Institute of Physiology, Academy of Sciences of the Ukrainian SSR, Kiev. Translated from Neirofiziologiya, Vol. 21, No. 2, pp. 204–210, March–April, 1989. |