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2021 Nobel Prize for mechanosensory transduction
Authors:Boris Martinac
Affiliation:Molecular Cardiology and Biophysics Division, Victor Chang Cardiac Research Institute and St. Vincent’s Medical School, Darlinghurst, NSW 2010 Australia
Abstract:Written by someone who has worked in the mechanobiology field for close to 40 years, this commentary describes some historical background to the recent award of one-half of the Nobel Prize for Physiology or Medicine to Ardem Patapoutian for his discovery of the family of mechanosensitive Piezo ion channels, which function as mechanoreceptors feeling the environment in senses such as touch, pain, and proprioception.
Keywords:Mechanosensitive ion channels   MscL   MscS   Piezo1   Piezo2
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