Steroid derivatives |
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| Authors: | R. Míčková J. Protiva V. Schwarz |
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| Affiliation: | 1. Research Institute for Pharmacy and Biochemistry, 194 04, Prague 9
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| Abstract: | Hydroxylation of l7α-acetoxy-6-chloro-16-methylene-4,6-pregnadiene-3,20-dione (Chlorosuperlutin, I) byCunninghamella blakesleeana yielded a 15β-hydroxyderivative II. Analogous transformation of 17α-acetoxy-16-methylene-4,6-pregnadiene-3,20-dione (Superlutin, IV) included a hydroxylation in position 15β and probably also in 11β with a concomitant reduction of the 6,7-double bond. |
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