In vitro tetracycline susceptibility of Chlamydia trachomatis in clinical specimens |
| |
Authors: | Anna H E Hsu Bernhard Knelsen Shanti Kasatiya |
| |
Institution: | (1) Public Health Laboratory, Ontario Ministry of Health, Station J, P.O. Box 6301, K1A 1S8 Ottawa, Ontario, Canada |
| |
Abstract: | A novel approach to determine the tetracycline susceptibility of Chlamydia trachomatis directly from specimens without cell culture propagation and adaptation has been explored. Out of a total of 1290 genital specimens from a sexually transmitted disease clinic, 211 (16.4%) were positive for C. trachomatis. A tetracycline concentration of 0.032 g/ml completely inhibited the appearance of inclusions in all of the 211 positive specimens. Of the positive specimens, 120 (56.9%) and 18 (8.5%) respectively showed the presence of 1 to 9 and 100 or more inclusions per microtiter well in antibiotic free medium. Other antibiotics are being tested in the same manner.A part of this paper was presented at the Canadian Public Health Association, STD meeting in Ottawa, Canada, 28–29 October 1985 |
| |
Keywords: | Chlamydia trachomatis tetracycline susceptibility cell culture microtest inclusions |
本文献已被 SpringerLink 等数据库收录! |
|