Insights into protein function through large-scale computational analysis of sequence and structure |
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Affiliation: | 1. Department of Pathology, New York Medical College, Valhalla, NY, USA;2. Department of Pathology and Clinical Laboratories, Westchester Medical Center, Valhalla, NY, USA;3. Philips Research North America, Briarcliff Manor, NY, USA;4. Division of Pediatric Infectious Disease, New York Medical College, Valhalla, NY, USA |
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Abstract: | Functional genomic and proteomic technologies are producing biological data relating to hundreds, or even thousands of proteins per experiment. Rapid and accurate computational analysis of the molecular function of these proteins is therefore crucial in order to interpret these data and prioritize further experiments. |
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