Quantitative Determination of Neuraminidase-Active Foci in Cell Monolayer Cultures Infected with Influenza or Newcastle Disease Virus |
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| Authors: | P Palese G Bodo and H Tuppy |
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| Institution: | Institut für Biochemie, University of Vienna, A-1090 Vienna, Austria;Arzneimittelforschung GmbH, A-1121 Vienna, Austria |
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| Abstract: | A synthetic neuraminidase substrate 2-(3'-methoxyphenyl)-N-acetyl-alpha-neuraminic acid] was used to detect myxo- and paramyxovirus replication in tissue culture. This method allowed estimation of viral growth even in the absence of cytopathogenic effects. |
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