Effects of dexamethasone on the levels of plasma corticosteroid binding globulin in rats and monkeys. |
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| Authors: | S Yamamoto N Ohsawa |
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| Affiliation: | Division of Hematology-Oncology, Childrens Hospital of Los Angeles and Departments of Pediatrics and Biochemistry, University of Southern California School of Medicine, Los Angeles, California 90027 USA |
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| Abstract: | Rat marrow cells were preincubated for 45 hours with 5.5 × 10?4M sodium hexachloroiridate. This treatment abolished DNA synthesis whilst improving cell survival over that of controls. The synthesis of RNA, protein and glycoprotein continued and could be further increased by the addition of erythropoietin for up to 44 more hours. Heme synthesis also continued in the absence of DNA synthesis but could not be stimulated by erythropoietin. |
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| Keywords: | EPO erythropoietin Ir sodium hexachloroiridate TCA trichloroacetic acid |
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