Differences in the ultrastructure of colored variants of colonies of pathogenic Neisseria

Electron-transparent zones (vacuoles) of different size and localization have been detected in the cytoplasm of meningococci forming orange colonies. These vacuoles have been detected in cells from meningococcal cultures of different age, grown both in liquid and solid culture media. This phenomenon requires further deeper study. The presence of a relationship between newly detected vacuoles and the pathogenicity of meningococci is suggested.