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AncestryPainter: A Graphic Program for Displaying Ancestry Composition of Populations and Individuals
Authors:Qidi Feng  Dongsheng Lu  Shuhua Xu
Affiliation:1. CAS Key Laboratory of Computational Biology, Max Planck Independent Research Group on Population Genomics, CAS-MPG Partner Institute for Computational Biology, Shanghai Institutes for Biological Sciences, Chinese Academy of Sciences, Shanghai 200031, China;2. University of Chinese Academy of Sciences, Beijing 100049, China;3. School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China;4. Center for Excellence in Animal Evolution and Genetics, Chinese Academy of Sciences, Kunming 650223, China;5. Collaborative Innovation Center of Genetics and Development, Shanghai 200438, China;6. Human Phenome Institute, Fudan University, Shanghai 201203, China
Abstract:Ancestry composition of populations and individuals has been extensively investigated in recent years due to advances in the genotyping and sequencing technologies. As the number of populations and individuals used for ancestry inference increases remarkably, say more than 100 populations or 1000 individuals, it is usually challenging to present the ancestry composition in a traditional way using a rectangular graph. To address this issue, we developed a program, AncestryPainter, which can illustrate the ancestry composition of populations and individuals with a rounded and nice-looking graph to save space. Individuals are depicted as length-fixed bars partitioned into colored segments representing different ancestries, and the population of interest can be highlighted as a pie chart in the center of the circle plot. In addition, AncestryPainter can also be applied to display personal ancestry in a way similar to that for displaying population ancestry. AncestryPainter is publicly available at http://www.picb.ac.cn/PGG/resource.php.
Keywords:Graphic program  Admixed populations  Ancestry composition  Admixture proportions
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