High‐throughput discovery of functional disordered regions |
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Authors: | Muhammad Ali Ylva Ivarsson |
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Institution: | Department of Chemistry – BMC, Uppsala University, Uppsala, Sweden |
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Abstract: | Partially or fully intrinsically disordered proteins are widespread in eukaryotic proteomes and play important biological functions. With the recognition that well defined protein structure is not a fundamental requirement for function come novel challenges, such as assigning function to disordered regions. In their recent work, Babu and colleagues (Ravarani et al, 2018 ) took on this challenge by developing IDR‐Screen, a robust high‐throughput approach for identifying functions of disordered regions. |
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