Changes in serum and synovial fluid biomarkers after acute injury (NCT00332254) |
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| Authors: | Jonathan B Catterall Thomas V Stabler Carl R Flannery Virginia B Kraus |
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| Institution: | (1) Division of Rheumatology, Department of Medicine, Duke University, Genome Science Research Building I, 905 South LaSalle Street, 27710 Durham, NC, USA;(2) Tissue Repair Research Unit, BioTherapeutics Division, Pfizer Inc, 200 Cambridge Park Drive, 02140 Cambridge, MA, USA |
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| Abstract: | Introduction Acute trauma involving the anterior cruciate ligament is believed to be a major risk factor for the development of post-traumatic
osteoarthritis 10 to 20 years post-injury. In this study, to better understand the early biological changes which occur after
acute injury, we investigated synovial fluid and serum biomarkers. |
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