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Single cell analysis applied to antibody fragment production with <Emphasis Type="Italic">Bacillus megaterium</Emphasis>: development of advanced physiology and bioprocess state estimation tools
Authors:Florian?David  Antje?Berger  Robert?H?nsch  Manfred?Rohde  Email author" target="_blank">Ezequiel?Franco-LaraEmail author
Institution:1.Institute of Biochemical Engineering, Technische Universit?t Braunschweig,Braunschweig,Germany;2.Botanical Institute, Technische Universit?t Braunschweig,Braunschweig,Germany;3.Helmholtz Centre for Infection Research Inhoffenstra?e 7,Braunschweig,Germany
Abstract:

Background  

Single cell analysis for bioprocess monitoring is an important tool to gain deeper insights into particular cell behavior and population dynamics of production processes and can be very useful for discrimination of the real bottleneck between product biosynthesis and secretion, respectively.
Keywords:
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