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Modeling operon dynamics: the tryptophan and lactose operons as paradigms
Authors:Mackey Michael C  Santillán Moisés  Yildirim Necmettin
Affiliation:Department of Physiology, Centre for Nonlinear Dynamics, McGill University, 3655 Drummond Street, Montreal, Quebec, Canada H3G 1Y6. mackey@cnd.mcgill.ca
Abstract:Understanding the regulation of gene control networks and their ensuing dynamics will be a critical component in the understanding of the mountain of genomic data being currently collected. This paper reviews recent mathematical modeling work on the tryptophan and lactose operons which are, respectively, the classical paradigms for repressible and inducible operons.
Keywords:gene regulatory networks  nonlinear dynamics  computational molecular biology  circuits de régulation des gènes  dynamique non linéaire  biologie moléculaire informatique
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