| Can modulation of endothelial nitric oxide synthase explain the vasculoprotective actions of statins? |
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| 引用本文： | Sessa WC. Can modulation of endothelial nitric oxide synthase explain the vasculoprotective actions of statins?[J]. Trends in molecular medicine, 2001, 7(5): 189-191. DOI: 10.1016/S1471-4914(01)01985-2 |
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| 作者姓名： | Sessa WC |
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| 摘 要： |
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Can modulation of endothelial nitric oxide synthase explain the vasculoprotective actions of statins? |
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| Sessa W C. Can modulation of endothelial nitric oxide synthase explain the vasculoprotective actions of statins?[J]. Trends in molecular medicine, 2001, 7(5): 189-191. DOI: 10.1016/S1471-4914(01)01985-2 |
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| Authors: | Sessa W C |
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| Affiliation: | Yale University School of Medicine, Dept of Pharmacology, Boyer Center for Molecular Medicine, 295 Congress Avenue, New Haven, CT 06536, USA. william.sessa@yale.edu |
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| Abstract: | Statin-based drugs are the mainstay of therapy for coronary artery disease. Recent insights into the cellular mechanisms of this class of drugs suggest that modulation of nitric oxide synthesis contributes to their beneficial actions. These effects are independent of their lipid-lowering effects and result in enhanced nitric oxide release. |
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