Cloning and characterization of the metallothionein-I gene from mouse LMTK cells |
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Authors: | R Brzezinski M Smorawinska G Vézina J Thibodeau J P Thirion |
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Affiliation: | Département de Microbiologie, Faculté de Médecine, Université de Sherbrooke, Québec, Canada. |
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Abstract: | A clone of about 14 kb containing the metallothionein MT-I gene and three repetitive sequences, was isolated from a genomic library of mouse LMTK DNA. The MT-I gene was functional. Transfected cells became cadmium resistant. Two of the three repetitive sequences were moderately repetitive while the other was closely related to the R family. |
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