Bifurcation analysis informs Bayesian inference in the Hes1 feedback loop |
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Authors: | Catherine F Higham |
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Institution: | (1) Faculty of Biomedical and Life Sciences, University of Glasgow, Glasgow, Scotland, UK |
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Abstract: | Background Ordinary differential equations (ODEs) are an important tool for describing the dynamics of biological systems. However, for
ODE models to be useful, their parameters must first be calibrated. Parameter estimation, that is, finding parameter values
given experimental data, is an inference problem that can be treated systematically through a Bayesian framework. |
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Keywords: | |
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