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Controlling selectivity of modular microbial biosynthesis of butyryl-CoA-derived designer esters
Institution:1. Bredesen Center for Interdisciplinary Research and Graduate Education, University of Tennessee, Knoxville, TN, USA;2. Center for Bioenergy Innovation, Oak Ridge National Laboratory, Oak Ridge, TN, USA;3. Department of Chemical and Biomolecular Engineering, University of Tennessee, Knoxville, TN, USA;1. Bredesen Center for Interdisciplinary Research and Graduate Education, The University of Tennessee, Knoxville and Oak Ridge National Laboratory, Oak Ridge, TN, USA;2. BioEnergy Science Center, Oak Ridge National Laboratory, Oak Ridge, TN, USA;3. Department of Chemical and Biomolecular Engineering, The University of Tennessee, Knoxville, TN, USA;4. Biosciecnes Division, Oak Ridge National Laboratory, Oak Ridge, TN, USA;5. Thayer School of Engineering, Dartmouth College, Hanover, NH, USA;1. State Key Laboratory of Food Science and Technology, Jiangnan University, Wuxi, 214122, China;2. International Joint Laboratory on Food Safety, Jiangnan University, Wuxi, 214122, China;3. Key Laboratory of Industrial Biotechnology, Ministry of Education, School of Biotechnology, Jiangnan University, Wuxi, 214122, China;4. Suzhou Microvac Biotech Co., Ltd., Suzhou, 215021, China;1. Department of Chemical Engineering, The Pennsylvania State University, University Park, PA, USA;2. Department of Bacteriology, University of Wisconsin—Madison, Madison, WI, USA;3. Thayer School of Engineering at Dartmouth College, Hanover, NH, USA;4. Center for Bioenergy Innovation, Oak Ridge, TN, USA
Abstract:
Keywords:Esters  Butyl acetate  Ethyl butyrate  Butyl butyrate  Alcohol acyltransferase  AAT  ATF1  SAAT  Modular design  Modular cell  Modular pathway design  Codon optimization  Fusion partners  Chaperones  Soluble expression  Enzyme solubilization
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