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Influence of dietary cod liver oil upon Trypanosoma congolense,T. cruzi,T. vivax and T. brucei
Authors:GODFREY D G
Affiliation:1. Department of Medical Parasitology, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt;2. Department of Medical Biochemistry, Faculty of Medicine, Taibah University, Saudi Arabia;3. Department of Biochemistry, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt;4. Department of Pathology, Faculty of Medicine, Mansoura University, Mansoura, 35516, Egypt;1. Department of Neurology, Korea University College of Medicine, 73 Inchon-ro, Seongbuk-gu, Seoul 136-705, Republic of Korea;2. Department of Obstetrics and Gynecology, Korea University College of Medicine, Seoul, Republic of Korea;3. Department of Cardiology, Korea University College of Medicine, Seoul, Republic of Korea;1. Department of Biological Sciences, University of Alberta, Edmonton, Alberta, Canada;2. Department of Microbiology and Immunology, University of Alberta, Edmonton, Alberta, Canada;1. State Key Laboratory of Biocontrol, Guangdong Province Key Laboratory for Aquatic Economic Animals, School of Life Sciences, Sun Yat-Sen University, Guangzhou, China;2. College of Animal Science, South China Agricultural University, Guangzhou, China;1. Instituto Carlos Chagas (ICC), Fundação Oswaldo Cruz (Fiocruz), Curitiba, Brazil;2. Instituto de Microbiologia Paulo de Góes (IMPG), Universidade Federal do Rio de Janeiro, Cidade Universitária, Rio de Janeiro, Brazil
Abstract:
  • 1.(i) Trypanosoma congolense multiplied more slowly in mice given a diet composed of casein, sucrose, dried yeast, salts, margarine and cod liver oil than in mice given a normal diet. This broadly confirms the report of Keppie (1953), except that the high degree of suppression reported by her was never observed in the present work.
  • 2.(ii) Cod liver oil given in diets adequate in water soluble vitamins suppressed the multiplication of T. congolense and vitamin E reversed this effect.
  • 3.(iii) T. vivax was markedly suppressed by a high cod liver diet and the suppression completely reversed by vitamin E.
  • 4.(iv) A high cod liver oil diet did not suppress T. cruzi, and it probably did not suppress T. brucei.
Keywords:
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