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PERIOD phosphorylation leads to feedback inhibition of CK1 activity to control circadian period
Institution:1. Department of Chemistry and Biochemistry, University of California, Santa Cruz, Santa Cruz, CA 95064, USA;2. Department of Biomedical Sciences, College of Medicine, Florida State University, Tallahassee, FL 32306, USA;3. Department of Chemistry and Biochemistry, University of California, San Diego, La Jolla, CA 92093, USA;4. Program in Cancer and Stem Cell Biology, Duke-NUS Medical School, Singapore 169857, Singapore;5. Department of Entomology and Nematology, University of California, Davis, Davis, CA 95616, USA;6. Department of Pharmacology, University of California, San Diego, La Jolla, CA 92093, USA;7. Department of Pediatrics, Duke University Medical Center, Durham, NC 27710, USA;8. Center for Circadian Biology, University of California, San Diego, La Jolla, CA 92093, USA
Abstract:
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  • Keywords:circadian rhythms  kinase  product inhibition  intrinsically disordered protein
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