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E3 Ubiquitin Ligase Fbw7 Negatively Regulates Osteoblast Differentiation by Targeting Runx2 for Degradation |
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| Authors: | Yogesh Kumar Isha Kapoor Kainat Khan Gatha Thacker Mohd Parvez Khan Nidhi Shukla Jitendra Kumar Kanaujiya Sabyasachi Sanyal Naibedya Chattopadhyay Arun Kumar Trivedi |
| Institution: | From the ‡Biochemistry Division, CSIR-Central Drug Research Institute (CSIR-CDRI), Sector-10, Jankipuram Extension, Lucknow, 226031 Uttar Pradesh and ;the §Division of Endocrinology and Center for Research in Anabolic Skeletal Targets in Health and Illness (ASTHI), CSIR-Central Drug Research Institute (CSIR-CDRI), Sector-10, Jankipuram Extension, Lucknow, 226031 Uttar Pradesh, India |
| Abstract: | |
| Keywords: | osteoblast proteasome protein degradation ubiquitin ligase ubiquitylation (ubiquitination) Runx2 Fbw7 GSK3-beta |