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Noncanonical processing by animal Microprocessor
Institution:1. Division of Life Science, The Hong Kong University of Science & Technology, Hong Kong, China;1. Max Planck Institute of Molecular Cell Biology and Genetics, Pfotenhauerstrasse 108, 01307 Dresden, Germany;2. Max Planck Institute for Brain Research, Max-von-Laue-Str. 4, 60438 Frankfurt am Main, Germany;3. Biomedical Research Institute, Foundation for Research and Technology, 45110 Ioannina, Greece;4. Laboratory of Biological Chemistry, Department of Medicine, School of Health Sciences, University of Ioannina, 45110 Ioannina, Greece;5. Center for Systems Biology Dresden, Pfotenhauerstrasse 108, 01307 Dresden, Germany;6. Department of Molecular Biology, University Medical Center Göttingen, Humboldtallee 23, 37073 Göttingen, Germany;7. Göttingen Centre for Molecular Biosciences, University of Göttingen, Justus-von-Liebig-Weg 11, 37077 Göttingen, Germany;8. Max Planck Institute for Multidisciplinary Sciences, Am Fassberg 11, 37077 Göttingen, Germany;1. Department of Metabolism and Nutritional Programming, Van Andel Institute, Grand Rapids, MI, USA;2. Metabolism and Nutrition (MeNu) Program, Van Andel Institute, Grand Rapids, MI, USA;3. Bioinformatics and Biostatistics Core, Van Andel Institute, Grand Rapids, MI, USA;4. Laura and Isaac Perlmutter Cancer Center, NYU Langone Health, New York, NY, USA;5. Department of Epigenetics, Van Andel Institute, Grand Rapids, MI, USA;1. Department of Chemistry and Chemical Biology, Harvard University, Cambridge, MA 02138, USA;2. Center for Mass Spectrometry, Harvard University, Cambridge, MA 02138, USA;1. Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, Boston, MA 02115, USA;1. Department of Molecular Biology and Genetics, Cornell University, Ithaca, NY 14853, USA;2. Department of Microbiology, Cornell University, Ithaca, NY 14853, USA;3. Department of Neurobiology, The University of Alabama at Birmingham, Birmingham, AL 35294, USA;1. Department of Structural Biochemistry, Max Planck Institute of Molecular Physiology, 44227 Dortmund, Germany;2. Max Planck Institute of Molecular Cell Biology and Genetics, 01307 Dresden, Germany;3. Center for Soft Nanoscience and Institute of Molecular Physics and Biophysics, 48149 Münster, Germany;4. Department of Mechanistic Cell Biology, Max Planck Institute of Molecular Physiology, 44227 Dortmund, Germany;5. Max Planck Institute for Multidisciplinary Sciences, 37077 Göttingen, Germany;6. Institute of Clinical Chemistry, University Medical Center Göttingen, 37075 Göttingen, Germany
Abstract:
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  • Keywords:Microprocessor  DROSHA  DGCR8  pri-miRNAs  miRNAs  canonical pri-miRNA processing  noncanonical pri-miRNA processing  DROSHA recognition sites  DRES
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