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Structure of the human ATP synthase
Institution:1. State Key Laboratory of Medicinal Chemical Biology and Frontiers Science Center for Cell Responses, College of Life Sciences, Nankai University, Tianjin 300071, China;2. Institute for Immunology, College of Life Sciences, Nankai University, Tianjin 300071, China;3. State Key Laboratory of Medicinal Chemical Biology, College of Pharmacy, Nankai University, Tianjin 300350, China;4. Shanghai Institute for Advanced Immunochemical Studies and School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China;5. School of Chemistry and Molecular Biosciences, The University of Queensland, Brisbane, QLD 4072, Australia;6. Innovative Center for Pathogen Research, Guangzhou Laboratory, Guangzhou 510005, China;7. National Laboratory of Biomacromolecules, CAS Center for Excellence in Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences (CAS), Beijing 100101, China;8. Laboratory of Structural Biology, Tsinghua University, Beijing 100084, China;1. Molecular Medicine Program, The Hospital for Sick Children, M5G 0A4, Toronto, Canada;2. Department of Biochemistry, The University of Toronto, M5G 1L7, Toronto, Canada;3. Department of Medical Biophysics, The University of Toronto, M5S 1A8, Toronto, Canada;1. Department of Cell and Developmental Biology, School of Molecular and Cellular Biology, University of Illinois-Urbana-Champaign, Urbana, IL, USA;1. Max-Planck Institute for Multidisciplinary Sciences, Laboratory of Biochemistry of Signal Dynamics, Göttingen, Germany;2. Institute of Molecular Medicine I, Medical Faculty and University Hospital Düsseldorf, Heinrich Heine University, Düsseldorf, Germany;3. Heidelberg University Biochemistry Center (BZH), Heidelberg, Germany;4. University Medical Centre Göttingen, Department of Cellular Biochemistry, Göttingen, Germany;5. Max-Planck Institute for Multidisciplinary Sciences, Bioanalytical Mass Spectrometry, Göttingen, Germany;6. University Medical Centre Göttingen, Institute of Clinical Chemistry, Bioanalytics Group, Göttingen, Germany;1. Sun Yat-sen University Cancer Center, State Key Laboratory of Oncology in South China, Collaborative Innovation Center for Cancer Medicine, Sun Yat-sen University, Guangzhou 510060, P. R. China;2. Research Department of Medical Sciences, Guangdong Provincial People’s Hospital, Guangdong Academy of Medical Sciences, Guangzhou 510060, P. R. China;3. Department of Pathology, Sun Yat-sen University Cancer Center, Guangzhou 510060, P. R. China;4. Department of Gastric Surgery, Sun Yat-sen University Cancer Center, Guangzhou, Guangdong 510060, P. R. China;5. Research Unit of Precision Diagnosis and Treatment for Gastrointestinal Cancer, Chinese Academy of Medical Sciences, Guangzhou 510060, P. R. China;1. Department of Biochemistry, School of Medicine, Southern University of Science and Technology, Shenzhen 518055, China;2. Key Laboratory of Molecular Design for Plant Cell Factory of Guangdong Higher Education Institutes, Department of Chemical Biology, School of Life Sciences, Southern University of Science and Technology, Shenzhen 518055, China;3. Shenzhen Key Laboratory of Cell Microenvironment, Guangdong Provincial Key Laboratory of Cell Microenvironment and Disease Research, Southern University of Science and Technology, Shenzhen 518055, China;4. Faculty of Pharmaceutical Sciences, Shenzhen Institutes of Advanced Technology, Chinese Academy of Science, Shenzhen 518055, China;5. Center for Human Tissues and Organs Degeneration, Shenzhen Institutes of Advanced Technology, Chinese Academy of Science, Shenzhen 518055, China;6. Key University Laboratory of Metabolism and Health of Guangdong, Southern University of Science and Technology, Shenzhen 518055, China
Abstract:
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  • Keywords:human ATP synthase  cryoelectron microscopy  Grotthus mechanism  proton translocation  symmetry mismatch  ATP synthase disease
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