Effects of chronic exposure to sodium arsenite on hypothalamo-pituitary-testicular activities in adult rats: possible an estrogenic mode of action |
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| Authors: | Kuladip Jana Subarna Jana Prabhat Kumar Samanta |
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| Affiliation: | (1) Department of veterinary Surgery and radiology, west Bengal University of Animal and Fishery Sciences, 37 and 68, K. B. Sarani, 700 037 Calcutta, West Bengal, India;(2) Institute of Molecular Medicine, Bengal Intelligent Park Ltd., Sector-V, Salt Lake Electronics Complex, 700 091 Calcutta, India |
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| Abstract: | Background Inorganic arsenic is a major water pollutant and a known human carcinogen that has a suppressive influence on spermatogenesis and androgenesis in male reproductive system. However, the actual molecular events resulting in male reproductive dysfunctions from exposure to arsenic remain unclear. In this context, we evaluated the mode of action of chronic oral exposure of sodium arsenite on hypothalamo-pituitary- testicular activities in mature male albino rats. |
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