Fast sequence evolution of Hox and Hox -derived genes in the genus Drosophila |
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| Authors: | Sònia Casillas Bárbara Negre Antonio Barbadilla Alfredo Ruiz |
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| Affiliation: | (1) Departament de Gentica i de Microbiologia, Universitat Autnoma de Barcelona, 08193 Bellaterra (Barcelona), Spain;(2) Department of Zoology, University of Cambridge, Cambridge, CB2 3EJ, UK |
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| Abstract: | Background It is expected that genes that are expressed early in development and have a complex expression pattern are under strong purifying selection and thus evolve slowly. Hox genes fulfill these criteria and thus, should have a low evolutionary rate. However, some observations point to a completely different scenario. Hox genes are usually highly conserved inside the homeobox, but very variable outside it. |
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