MannDB – A microbial database of automated protein sequence analyses and evidence integration for protein characterization |
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| Authors: | L Ecale Carol Zhou Marisa W Lam Jason R Smith Adam T Zemla Matthew D Dyer Thomas A Kuczmarski Elizabeth A Vitalis Thomas R Slezak |
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| Affiliation: | (1) Lawrence Livermore National Laboratory, Pathogen Bio-informatics, Livermore, CA, USA;(2) Virginia Bioinformatics Institute, Virginia Polytechnic Institute and State University, Blacksburg, VA, USA |
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| Abstract: | Background MannDB was created to meet a need for rapid, comprehensive automated protein sequence analyses to support selection of proteins suitable as targets for driving the development of reagents for pathogen or protein toxin detection. Because a large number of open-source tools were needed, it was necessary to produce a software system to scale the computations for whole-proteome analysis. Thus, we built a fully automated system for executing software tools and for storage, integration, and display of automated protein sequence analysis and annotation data. |
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