Evolutionary constraints on yeast protein size |
| |
Authors: | Jonas Warringer Anders Blomberg |
| |
Institution: | (1) Department of Cell and Molecular Biology, Lundberg Laboratory, Gteborg University Medicinaregatan 9c, 41390 Gteborg, Sweden |
| |
Abstract: | Background Despite a strong evolutionary pressure to reduce genome size, proteins vary in length over a surprisingly wide range also
in very compact genomes. Here we investigated the evolutionary forces that act on protein size in the yeast Saccharomyces cerevisiae utilizing a system-wide bioinformatics approach. Data on yeast protein size was compared to global experimental data on protein
expression, phenotypic pleiotropy, protein-protein interactions, protein evolutionary rate and biochemical classification. |
| |
Keywords: | |
本文献已被 SpringerLink 等数据库收录! |
|