益生菌在炎症性肠病治疗中的研究进展

益生菌（Probiotics）是一类能够促进肠道微生物菌群平衡,对宿主健康或生理功能产生有益作用的活性微生物。目前广泛应用于生命健康领域、科学研究、生物工程、工农业以及食品安全。大量国内外研究表明益生菌在降血压、降血糖、降血脂、抗过敏、抗炎、调节免疫、维持肠道菌群平衡等方面具有积极作用。炎症性肠病的病因和发病机制尚未完全明确,现多认为与遗传、环境、感染、免疫以及肠道微生物多因素相互作用有关。益生菌通过多种机制介导,在临床治疗炎症性肠病中扮演着重要角色。

Advances of researches on probiotics in the treatment of inflammatory bowel disease

Probiotics have been defined as living microorganisms that may promote the ecological balance of intestinal bacteria and exert beneficial effects on the health or physiological function of the host. Probiotics have been widely used in scientific study, healthcare, biological engineering, industry-agriculture and food safety currently. A large number of researches have shown that probiotics play positive roles in lowering blood glucose, blood pressure and blood fat, anti-allergy, anti-inflammation, immune regulation and maintaining the balance of intestinal flora. The etiology and pathogenesis of inflammatory bowel disease are not fully undersood, and may have relations with the interaction of heredity, environment, infections, immunity and intestinal flora. Probiotics play an important role in the d treatment of inflammatory bowel disease through multiple mechanisms.