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Design and semisynthesis of spermine-sensitive Ribonuclease S'. |
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| Authors: | I Hamachi Y Yamada R Eboshi T Hiraoka S Shinkai |
| Institution: | Department of Chemistry & Biochemistry, Graduate School of Engineering, Kyushu University, Hakozaki, Fukuoka, Japan. |
| Abstract: | Spermine-sensitive stabilization of semisynthetic Ribonuclease S' was successfully carried out by sequence specific incorporation of a poly-anion domain into alpha-helix region of S-peptide. |
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