Antimicrobial activity of diterpene resin acid derivatives. |
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| Authors: | S Savluchinske Feio B Gigante J C Roseiro M J Marcelo-Curto |
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| Affiliation: | Instituto Nacional de Engenharia e Tecnologia Industrial, IBQTA, Laboratório de Microbiologia Industrial, Azinhaga dos Lameiros, Lisboa, Portugal. |
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| Abstract: | C-13 deisopropylated and/or C-7 oxidized resin acid derivatives were tested against various microorganisms to determine structural features responsible for biological activity and to determine the influence of the C-13 isopropyl group on antimicrobial activity. Test results show that methyl cis and trans 7-oxo-13-deisopropyldehydroabietate and a mixture of both isomers exhibited activity against fungi and bacteria. |
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