| 贵金属-磁性异质结构纳米材料及其生物医学应用 |
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| 引用本文： | 周旖旎,徐庆,苏丹,苏拓,王炜,余靓. 贵金属-磁性异质结构纳米材料及其生物医学应用[J]. 生物化学与生物物理进展, 2020, 47(5): 371-385 |
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| 作者姓名： | 周旖旎 徐庆 苏丹 苏拓 王炜 余靓 |
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| 作者单位： | 浙江工业大学材料科学与工程学院磁电功能材料研究所,浙江工业大学材料科学与工程学院磁电功能材料研究所,浙江省人民医院,浙江工业大学材料科学与工程学院磁电功能材料研究所,浙江工业大学材料科学与工程学院磁电功能材料研究所,浙江工业大学材料科学与工程学院磁电功能材料研究所 |
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| 基金项目： | 浙江省自然科学基金、国家自然科学基金、中国科协青年人才托举工程、清华大学先进材料教育部重点实验室开放基金、浙江省属高校基本科研业务费专项、浙江省卫生厅 |
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| 摘 要： | 异质结构纳米颗粒不仅可以同时拥有多种单组分纳米颗粒不同的性能,实现多功能化,还可能因组分间的相互耦合作用而产生单组分颗粒不具备的新性能,因而在化学化工、生物医学、能源催化等领域引起广泛关注.贵金属具有特殊的光学性质和催化活性;磁性纳米颗粒拥有优异的磁性能,因而备受研究人员关注.贵金属-磁性异质结构纳米材料集合了两种材料优异的性能,能通过不同的异质结构展现出不同的性质.本文根据异质结构的类型,将贵金属-磁性异质结构纳米材料分为核壳结构、蛋黄-壳结构和哑铃结构3种,总结了不同贵金属-磁性异质结构纳米颗粒的特性、制备方法及应用,并重点论述了其在诊疗一体化探针、多模态成像探针和刺激响应型药物载体生物医学领域上的应用.
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| 关 键 词： | 贵金属-磁性异质结构 核壳结构 蛋黄壳结构 哑铃结构 生物医学应用 |
| 收稿时间： | 2019-11-15 |
| 修稿时间： | 2020-03-05 |
Biomedical Applications of Noble Metal-Magnetic Heterogeneous Nanoparticles |
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| ZHOU Yi-Ni,XU Qing,SU Dan,SU Tuo,WANG Wei and YU Jing. Biomedical Applications of Noble Metal-Magnetic Heterogeneous Nanoparticles[J]. Progress In Biochemistry and Biophysics, 2020, 47(5): 371-385 |
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| Authors: | ZHOU Yi-Ni XU Qing SU Dan SU Tuo WANG Wei YU Jing |
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| Affiliation: | Research Center of Magnetic and Electronic Materials, College of Materials Science and Engineering, Zhejiang University of Technology,Research Center of Magnetic and Electronic Materials, College of Materials Science and Engineering, Zhejiang University of Technology,Department of Oncology, Zhejiang Provincial People''s Hospital,Research Center of Magnetic and Electronic Materials, College of Materials Science and Engineering, Zhejiang University of Technology,Research Center of Magnetic and Electronic Materials, College of Materials Science and Engineering, Zhejiang University of Technology,Research Center of Magnetic and Electronic Materials, College of Materials Science and Engineering, Zhejiang University of Technology |
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| Abstract: | Heterostructure nanoparticles (NPs) which are composed of different ingredients, appear multiple performances that induced by each component. It is also possible to produce new properties that are not available for single-component particles, due to the mutual coupling between different components. As a result, heterostructure NPs have attracted extensive attention in the field of chemical engineering, biomedicine, and energy catalysis. Due to the special optical properties and catalytic activity of noble metals, and the excellent magnetic properties of magnetic nanoparticles, noble metal-magnetic heterogeneous nanoparticles have attracted much attention from researchers. These nanomaterials combine the excellent properties of the two materials and exhibit different properties through different heterostructures. In this review, noble metal-magnetic heterogeneous nanomaterials were classified into core-shell structure, yolk-shell structure, and dumbbell structure by their structures, and their characteristics, preparation methods and applications were summarized. Their applications in biomedicine, including theranostics, multimode imaging and stimuli-responsive drug carriers, were particularly emphasized. |
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| Keywords: | noble metal-magnetic heterogeneous nanoparticles core-shell yolk-shell dumbbell-like biomedical application |
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