Patterns of intron sequence evolution in Drosophila are dependent upon length and GC content |
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| Authors: | Penelope R Haddrill Brian Charlesworth Daniel L Halligan and Peter Andolfatto |
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| Institution: | (1) Institute of Evolutionary Biology, School of Biological Sciences, University of Edinburgh, Edinburgh, EH9 3JT, UK;(2) Section of Ecology, Behavior and Evolution, Division of Biological Sciences, University of California San Diego, La Jolla, CA 92093, USA |
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| Abstract: | Background Introns comprise a large fraction of eukaryotic genomes, yet little is known about their functional significance. Regulatory
elements have been mapped to some introns, though these are believed to account for only a small fraction of genome wide intronic
DNA. No consistent patterns have emerged from studies that have investigated general levels of evolutionary constraint in
introns. |
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