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Micropatterned carbohydrate displays by self-assembly of glycoconjugate polymers on hydrophobic templates on silicon
Authors:Miura Yoshiko  Sato Hajime  Ikeda Takayasu  Sugimura Hiroyuki  Takai Osamu  Kobayashi Kazukiyo
Affiliation:Department of Molecular Design and Engineering, Graduate School of Engineering, Nagoya University, Furo-cho, Chikusa-ku, 464-8603, Japan. miuray@mol.nagoya-u.ac.jp
Abstract:We report a novel strategy for micropatterned carbohydrate displays on Si substrates. This method exploited the hydrophobic-hydrophilic microfabrication by photolithography of ODS-SAM on Si substrates and the subsequent selective self-assembly of glycoconjugate polymers onto the hydrophobic regions. Protein micropatterning by molecular recognition on the carbohydrate substrates was also successful.
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