| 果蝇生殖腺干细胞和它们的微环境 |
| |
| 引用本文： | 冯振月,潘敏慧,鲁成. 果蝇生殖腺干细胞和它们的微环境[J]. 细胞生物学杂志, 2006, 28(2): 169-172 |
| |
| 作者姓名： | 冯振月 潘敏慧 鲁成 |
| |
| 作者单位： | 西南大学蚕学与生物技术学院、农业部蚕桑学重点实验室,重庆400716 |
| |
| 基金项目： | 科技部科研项目;中国科学院资助项目 |
| |
| 摘 要： | 干细胞微环境是由容纳一个或多个干细胞，并控制干细胞自我更新和子代细胞产生的组织细胞以及细胞外基质组成。干细胞必须在微环境内才能增殖，才能保持自我更新的特性。通过对果蝇生殖腺干细胞微环境的结构及其产生的信号路径（该路径可以调节干细胞自我更新）的研究，发现微环境中支持细胞和它们发出的信号路径在调节干细胞的增殖和分化中起重要的作用。
|
| 关 键 词： | 果蝇 干细胞 微环境 信号路径 |
| 收稿时间： | 2005-08-12 |
| 修稿时间： | 2005-10-17 |
Drosophila Germline Stem Cells and Their Microenvironment |
| |
| Zhen-Yue Feng,Min-Hui Pan,Cheng Lu. Drosophila Germline Stem Cells and Their Microenvironment[J]. Chinese Journal of Cell Biology, 2006, 28(2): 169-172 |
| |
| Authors: | Zhen-Yue Feng Min-Hui Pan Cheng Lu |
| |
| Affiliation: | Key Sericultural Laboratory of Agriculture Ministry, College of Sericulture and Biotechnology, Southwest University, Chongqing 400716, China |
| |
| Abstract: | Stem cells microenvironment is considered to substrates that can indefinitely house one or more stem cells and be composed of tissue cells and extracellular control their self-renewal and prevents their differentiation. Stem cells can only multiply and maintain self-renewal in a specific niche. Studies using the model biology Drosophila germline stem cells niche system have revealed that support cells and their signaling pathways in the microenvironment play a vital role in controlling the fate of the stem cells. |
| |
| Keywords: | Drosophila germline stem ceils microenvironment signaling pathways |
| 本文献已被 CNKI 维普 万方数据 等数据库收录！ |
