Characterization of selenium status of inhabitants in the region Ústi nad orlici,czech republic by inaa of blood serum and hair and fluorimetric analysis of urine |
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Authors: | Kvícala Jan Zamrazil Václav Jiránek Václav |
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Institution: | (1) Institute of Endocrinology, Národni 8, 116 94 Praha 1, Czech Republic;(2) DataPro, Radiouá 1, 102 27 Praha 10, Czech Republic |
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Abstract: | Selenium is an essential trace element and its isufficient status may cause serious health complications for both individuals
and the whole populations. To investigate the selenium status of the subpop-ulation in northeastern Bohemia represented by
the region ústí nad Orlicí, 253 serum, 469 urine, and 31 hair samples from 470 randomly selected volunteers between 6 and
65 yr of age have been analyzed for selenium concentration. Serum and hair Se were detected by instrumental neutron activation
analysis (means: 55 ±11 Μg Se/L sera, 0.268 ±0.040 Μg Se/g hair). Urine Se was measured by fluorimetry (12 ±5 Μg Se/L urine)
with coanalyses of Lyphocheck urine, SRM Urine 2670, and Seronorm urine for quality control of the method. Results proved
significant age-dependent differences, but gender differences were not significant. The frequency plot of serum Se proved
maximal frequencies in adults between 55 and 70 Μg Se/L and in children in the range 45–55 Μg Se/L. The same plots of urine
Se for both age groups showed maximal frequency in the limits 8–15 Μg Se/L. All indices used (Se in serum, urine, and hair)
confirmed mild to severe selenium deficiency in the population of the region. |
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Keywords: | Selenium status serum selenium urine selenium hair selenium selenium deficiency age and gender selenium intake |
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