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Anti-proliferative effects of isosclerone isolated from marine fungus Aspergillus fumigatus in MCF-7 human breast cancer cells
Affiliation:1. Marine Bioprocess Research Center, Pukyong National University, Busan 608-737, Republic of Korea;2. Department of Chemistry, Pukyong National University, Busan 608-737, Republic of Korea;3. Specialized Graduate School Science and Technology Convergence, Department of Marine Bio Convergence Science, Pukyong National University, Busan 608-737, Republic of Korea;1. Palladin Institute of Biochemistry NAS of Ukraine, Ukraine;2. Brighton University, Brighton, UK;1. Department of Neurochemistry, Tohoku University Graduate School of Medicine, 2-1 Seiryocho, Aoba-ku, Sendai 980-8575, Japan;2. Department of Nanostructure and Advanced Materials, Graduate School of Science and Engineering, Kagoshima University, 1-21-40 Kohrimoto, Kagoshima 890-0065, Japan;1. University of Calgary, Calgary, Alberta, Canada;2. Canadian Space Agency, Saint-Hubert, Quebec, Canada;3. MDA Corporation, Richmond, British Columbia, Canada;1. Department of Cosmetic Science, Chang Gung University of Science and Technology, Tao-Yuan 33344, Taiwan;2. National Research Institute of Chinese Medicine, Taipei 11221, Taiwan;3. Department of Chinese Pharmaceutical Sciences and Chinese Medicine Resources, China Medical University, Taichung 404, Taiwan;4. Department of Biotechnology, Asia University, Taichung 413, Taiwan;5. Department of Biotechnology, HungKuang University, Taichung 43302, Taiwan;6. Department of Nursing, HungKuang University, Taichung City 43302, Taiwan
Abstract:
Keywords:Isosclerone  Anti-proliferation  MMP-2 and -9  MAPK signaling pathway  P53 family proteins
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