Mucocutaneous leishmaniasis as presentation of HIV infection in Sardinia,insular Italy |
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| Institution: | 1. Department of Clinical and Experimental Medicine, University of Sassari, Italy;2. Department of Surgical, Microsurgical and Medical Sciences, University of Sassari, Italy;3. Department of Clinical and Molecular Biomedicine, University of Catania, Italy;1. Department of Medical Parasitology and Mycology, Shahid Beheshti University of Medical Sciences, Tehran, Iran;2. Department of Medical Parasitology and Mycology, Lorestan University of Medical Sciences, Khorramabad, Iran;3. Department of Biotechnology, Shahid Beheshti University of Medical Sciences, Tehran, Iran;4. Department of Medical Parasitology and Mycology, School of Public Health, Tehran University of Medical Sciences, Tehran, Iran;5. Institute of Cancer, Tehran Medical Center of Children with Cancer, Tehran, Iran;1. Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), Biopolis, 136648 Singapore;2. Department of Microbiology, Yong Loo Lin School of Medicine, National University of Singapore, Singapore;1. Laboratorio de Zoonosis Parasitarias, Departamento de Biología, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata (UNMdP), Funes 3350, Nivel Cero, 7600 Mar del Plata, Argentina;2. Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina;3. Laboratorio de Bioquímica Farmacológica, Instituto de Bioquímica y Microbiología, Facultad de Ciencias, Universidad Austral de Chile, Campus Isla Teja, Valdivia, Chile;4. Departamento de Química, Facultad de Ciencias Exactas y Naturales, Universidad Nacional de Mar del Plata (UNMdP), Funes 3350, Nivel 2, 7600 Mar del Plata, Argentina |
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| Abstract: | Leishmaniasis is endemic in Sardinia but only cutaneous and visceral cases have been reported to date. We report a case of mucocutaneous leishmaniasis as presentation of HIV infection in a Sardinian patient who had never visited endemic areas. Serological and clinical diagnosis was cytologically and histopathologically confirmed. The patient had a good response to treatment with liposomal amphotericin combined with highly active antiretroviral therapy without recurrences after four years. Our case report highlights the need to better assess the circulation of species, risk factors and clinical spectrum of Leishmania infection in the Italian Mediterranean islands. |
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