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Contamination of Indian maize with fumonisin B1 and its effects on chicken macrophage
Authors:D Chatterjee  SK Mukherjee
Institution:Department of Food Technology and Biochemical Engineering, Jadavpur University, Calcutta, India
Abstract:The natural occurrence of fumonisin B1 (FB1) in Indian maize and its impact on the viability and phagocytosis of chicken peritoneal macrophages in vitro were investigated. FB1 was found to be present at the levels of 300–366 ppm in Fusarium moniliforme -infected maize grains. The infected kernels in a population of 100 ears showed normal (Gaussian) frequency distribution. FB1, extracted from the contaminated kernels, reduced the viability and phagocytic activity of macrophages. These findings imply that FB1 exposure may become a potential problem in India and may lead to decreased immune responses with consequent susceptibility of a host to infection.
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