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A-seco-oleane-type triterpenes from Phomopsis sp. (strain HKI0458) isolated from the mangrove plant Hibiscus tiliaceus
Authors:Li Liya  Sattler Isabel  Deng Zhiwei  Groth Ingrid  Walther Grit  Klaus-Dieter Menzel  Peschel Gudrun  Grabley Susanne  Lin Wenhan
Institution:State Key Laboratory of Natural and Biomimetic Drugs, Peking University, Beijing 100083, PR China.
Abstract:From the fermentation broth of an unidentified Phomopsis sp. (strain HKI0458) isolated from the mangrove plant Hibiscus tiliaceus, four A-seco-oleane-type triterpenes, namely 3,4-seco-olean-11,13-dien-4,15alpha, 22beta,24-tetraol-3-oic acid (1), 3,4-seco-olean-11,13-dien-4,7beta,22beta,24-tetraol-3-oic acid (2), 3,4-seco- olean-13-en-4,7,15,22,24-pentaol-3-oic acid (3), and 3,4-seco-olean-13-en-4,15,22,24-tetraol-3-oic acid (4) were obtained. Their structures were elucidated by extensive spectroscopic (UV, IR, FABMS, and 2D NMR) data analyses.
Keywords:Fungus  Phomopsis sp    Mangrove plant  Hibiscus tiliaceus  Malvaceae  A-seco-oleane-type triterpenes  Spectroscopic analyses
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