A pyruvate decarboxylase gene from Aspergillus parasiticus |
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| Authors: | Vicente Sanchis Inmaculada Vinas Ian N. Roberts David J. Jeenes Adrian J. Watson David B. Archer |
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| Affiliation: | Institute of Food Research, Norwich Research Park, Colney, Norwich NR4 7UA, UK |
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| Abstract: | Abstract A gene encoding a putative pyruvate decarboxylase (EC 4.1.1.1) was isolated from a genomic library of the filamentous fungus Aspergillus parasiticus strain SU-1. The deduced amino acid sequence showed 37% homology to PDC1 from Saccharomyces cerevisiae . Although A. parasiticus has an obligate growth requirement for oxygen, it produced ethanol in shake flask cultures indicating a response to anoxic conditions mediated by pyruvate decarboxylase. |
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| Keywords: | Aspergillus parasiticus Ethanol Pyruvate decarboxylase |
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