|
|||||
|
|
Kinetic Investigations of the Role of Factor Inhibiting Hypoxia-inducible Factor (FIH) as an Oxygen Sensor |
|
| Authors: | Hanna Tarhonskaya Adam P. Hardy Emily A. Howe Nikita D. Loik Holger B. Kramer James S. O. McCullagh Christopher J. Schofield Emily Flashman |
| Affiliation: | From the ‡Chemistry Research Laboratory, University of Oxford, 12 Mansfield Road, Oxford OX1 3TA, United Kingdom and ;the §OXION Proteomics Facility, Department of Physiology, Anatomy, and Genetics, University of Oxford, South Parks Road, Oxford OX1 3QX, United Kingdom |
| Abstract: | |
| Keywords: | dioxygenase hypoxia hypoxia-inducible factor (HIF) kinetics pre-steady-state kinetics HIF hydroxylase ankyrin repeat domain factor inhibiting HIF oxygen sensor prolyl hydroxylase |