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Identification of in vitro and in vivo disconnects using transcriptomic data |
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| Authors: | Martin Otava Ziv Shkedy Willem Talloen Geert R Verheyen Adetayo Kasim |
| Affiliation: | .Interuniversity Institute for Biostatistics and Statistical Bioinformatics, Hasselt University, Martelarenlaan 32, Hasselt, 3500 Belgium ;.Janssen, Pharmaceutical companies of Johnson & Johnson, Turnhoutseweg 30, Beerse, 2340 Belgium ;.Thomas More Kempen, Geel, 2440 Belgium ;.Wolfson Research Institute for Health and Wellbeing, Durham University, University Boulevard, TS17 6BH Thornaby, Stockton-on-Tees, UK |
| Abstract: | |
| Keywords: | in vitro in vivo Toxicogenomics Gene expression Dose-response relationship Liver toxicity |