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Phosphorylation of the Hippo Pathway Component AMOTL2 by the mTORC2 Kinase Promotes YAP Signaling,Resulting in Enhanced Glioblastoma Growth and Invasiveness |
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| Authors: | Nicholas Artinian Cheri Cloninger Brent Holmes Angelica Benavides-Serrato Tariq Bashir Joseph Gera |
| Affiliation: | From the ‡Department of Medicine, David Geffen School of Medicine at UCLA.;¶Jonnson Comprehensive Cancer Center, and ;‖Molecular Biology Institute, UCLA, Los Angeles, California 90048 and ;the §Department of Research and Development, Greater Los Angeles Veterans Affairs Healthcare System, Los Angeles, California 91343 |
| Abstract: | |
| Keywords: | glioblastoma Hippo pathway mechanistic target of rapamycin (mTOR) mTOR complex (mTORC) yes-associated protein (YAP) AMOTL2 mTORC2 |