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A BAHD acyltransferase catalyzing 19‐O‐acetylation of tabersonine derivatives in roots of Catharanthus roseus enables combinatorial synthesis of monoterpene indole alkaloids |
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| Authors: | Inês Carqueijeiro Thomas Dugé de Bernonville Arnaud Lanoue Thu‐Thuy Dang Christiana N Teijaro Christian Paetz Kevin Billet Angela Mosquera Audrey Oudin Sébastien Besseau Nicolas Papon Gaëlle Glévarec Lucía Atehortùa Marc Clastre Nathalie Giglioli‐Guivarc'h Bernd Schneider Benoit St‐Pierre Rodrigo B. Andrade Sarah E. O'Connor Vincent Courdavault |
| Affiliation: | 1. EA2106 ‘Biomolécules et Biotechnologies Végétales’, Université de Tours, Tours, France;2. Department of Biological Chemistry, The John Innes Centre, Norwich, UK;3. Department of Chemistry, Temple University, Philadelphia, Pennsylvania, USA;4. Max‐Planck‐Institute for Chemical Ecology, Beutenberg Campus, Jena, Germany;5. Laboratorio de Biotecnología, Universidad de Antioquia, Sede de Investigación Universitaria, Medellin, Colombia;6. EA3142 ‘Groupe d'Etude des Interactions H?te‐Pathogène’, Université d'Angers, Angers, France |
| Abstract: | |
| Keywords: | acetyltransferase BAHD acyltransferase alkaloids Catharanthus roseus combinatorial biosynthesis metabolic engineering tabersonine |