Oligonucleotide interactions. I. Structure of 2:1 complexes between polyuridylic acid and oligoadenylic acid

The circular dichroism of a number of 1:2 complexes between oligoadenylic acid and polyuridylic acid has been measured. The structure of these complexes, as evidenced by their optical properties, is independent of the chain length of the oligonucleotide throughout all ranges of chain lengths from adenosine to high molecular weight polyadenylic acid. A similar structure was found for the complex (Ap)₅A:2(Up)₅U.