昆虫分子生物学的一些进展：神经递质和离子通道

昆虫分子生物学的一些进展：神经递质和离子通道翟启慧（中国科学院动物研究所北京１０００８０）１神经递质神经递质（ｎｅｕｒｏｔｒａｎ。ｍｉｔｔｅｒ）是在化学突触神经ｆＧ。１问传递信息的化学物质。神经递质有许多不同类型，如乙酸胆碱、丫一氨基丁酸、生物胺等。...

SOME ASPECTS OF PROGRESS IN INSECT MOLECULAR BIOLOGY: NEUROTRANSMITTERS AND ION CHANNELS

This paper is the third part of a review on recent progress in insect molecular biology. It surveys recent information on insect genes related to neurotransmitters and ion channels.Because neurotransmitters and ion channels play key roles in the transmission of chemical and electrical signals in insect nervous system, one of the major goals of insect neurobiology has been to study genes related to the structure, metabolism and function of neurotransmitters and ion channels. Some of the insect neurotransmitters and ion channels are targets of insecticide action, and' the study on the neurotransmitter-related genes and ion channel genes is also a prerequisite for investigating resistance genes.The present article summarizes information on the genes involved in the cholinergic system (ChAT, AchE and AchR), GABAergic system (GAD and GABA receptor) and biogenic amine (serotonin receptor). For the ion channels, molecular aspects of the two major voltage-gated ion channels-sodium and potassium channel genes are reviewed.