High resolution crystal structure of PedB: a structural basis for the classification of pediocin-like immunity proteins |
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| Authors: | In-Kwon Kim Min-Kyu Kim Ji-Hye Kim Hyung-Soon Yim Sun-Shin Cha Sa-Ouk Kang |
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| Institution: | (1) Laboratory of Biophysics, School of Biological Sciences, and Institute of Microbiology, Seoul National University, Seoul, 151-742, Republic of Korea;(2) Beamline Division, Pohang Accelerator Laboratory, Pohang, 790-784, Republic of Korea |
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| Abstract: | Background Pediocin-like bacteriocins, ribosomally-synthesized antimicrobial peptides, are generally coexpressed with cognate immunity
proteins in order to protect the bacteriocin-producer from its own bacteriocin. As a step for understanding the mode of action
of immunity proteins, we determined the crystal structure of PedB, a pediocin-like immunity protein conferring immunity to
pediocin PP-1. |
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