Adiponectin and AMP kinase activator stimulate proliferation,differentiation, and mineralization of osteoblastic MC3T3-E1 cells |
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| Authors: | Ippei Kanazawa Toru Yamaguchi Shozo Yano Mika Yamauchi Masahiro Yamamoto Toshitsugu Sugimoto |
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| Institution: | (1) Department of Internal Medicine 1, Shimane University School of Medicine, Tottori, Japan |
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| Abstract: | Background Adiponectin is a key mediator of the metabolic syndrome that is caused by visceral fat accumulation. Adiponectin and its receptors
are known to be expressed in osteoblasts, but their actions with regard to bone metabolism are still unclear. In this study,
we investigated the effects of adiponectin on the proliferation, differentiation, and mineralization of osteoblastic MC3T3-E1
cells. |
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